A retrospective Overview of Monkeypox Vs Smallpox

Abstract

This review paper provides an in-depth comparison of Monkeypox virus (MPXV) and Smallpox virus (variola virus) in terms of their origin, epidemiology, virus structure and genome, clinical features and diagnosis, transmission and prevention, and public health implications. While Smallpox virus has been eradicated, the potential threat of its use as a biological weapon has necessitated ongoing research and preparedness efforts. Meanwhile, MPXV continues to pose a threat in some parts of the world, with sporadic outbreaks reported in Central and West Africa. The paper highlights the unique characteristics of each virus and the implications of these differences for public health policy and future research. The study of these viruses underscores the importance of ongoing infectious disease research, collaboration among researchers, public health officials, and policymakers, and the need for continued vigilance and monitoring of emerging infectious diseases. Additionally, vaccination remains a crucial public health intervention for reducing the threat of future outbreaks.